The boron neutron capture therapy(BNCT) is a promising method of cancer treatment in principle, which kills cancer cells selectively by the use of cancer seeking boron compound and the neutron irradiation. This therapy has been expected very effective for the malignant brain tumor - glioblastoma multiforme for which any treatment tried by human has not been successful yet, and the researches on this therapy has been performed in many countries. The ENF can be used for the local irradiation treatment method and for the pre-clinical trials such as small animal irradiation.